Article
Copper-transporting ATPase is important for malaria parasite fertility.
Molecular microbiology - 1 Jan 2014
Kenthirapalan Sanketha, Waters Andrew P, Matuschewski Kai, Kooij Taco W A
Abstract excerpt
Homeostasis of the trace element copper is essential to all eukaryotic life. Copper serves as a cofactor in metalloenzymes and catalyses electron transfer reactions as well as the generation of potentially toxic reactive oxygen species. Here, we describe the functional characterization of an evolutionarily highly conserved, predicted copper-transporting P-type ATPase (CuTP) in the murine malaria model parasite...
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