Article
Preliminary biomarkers for identification of human ascending thoracic aortic aneurysm.
Journal of the American Heart Association - 14 Nov 2013
Black Kendra M, Masuzawa Akihiro, Hagberg Robert C, Khabbaz Kamal R, Trovato Mary E, Rettagliati Verna M, Bhasin Manoj K, Dillon Simon T, Libermann Towia A, Toumpoulis Ioannis K, Levitsky Sidney, McCully James D
Abstract excerpt
BACKGROUND: Human ascending thoracic aortic aneurysms (ATAAs) are life threatening and constitute a leading cause of mortality in the United States. Previously, we demonstrated that collagens α2(V) and α1(XI) mRNA and protein expression levels are significantly increased in ATAAs. METHODS AND RESULTS: In this report, the authors extended these preliminary studies using high-throughput proteomic analysis to...
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