Article
A review for detecting gene-gene interactions using machine learning methods in genetic epidemiology.
BioMed research international - 1 Jan 2013
Koo Ching Lee, Liew Mei Jing, Mohamad Mohd Saberi, Salleh Abdul Hakim Mohamed
Abstract excerpt
Recently, the greatest statistical computational challenge in genetic epidemiology is to identify and characterize the genes that interact with other genes and environment factors that bring the effect on complex multifactorial disease. These gene-gene interactions are also denoted as epitasis in which this phenomenon cannot be solved by traditional statistical method due to the high dimensionality of the data...
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