Article
Genomewide association study in cervical dystonia demonstrates possible association with sodium leak channel.
Movement disorders : official journal of the Movement Disorder Society - 1 Feb 2014
Mok Kin Y, Schneider Susanne A, Trabzuni Daniah, Stamelou Maria, Edwards Mark, Kasperaviciute Dalia, Pickering-Brown Stuart, Silverdale Monty, Hardy John, Bhatia Kailash P
Abstract excerpt
Dystonia is a common movement disorder. A number of monogenic causes have been identified. However, the majority of dystonia cases are not explained by single gene defects. Cervical dystonia is one of the commonest forms without genetic causes identified. This pilot study aimed to identify large effect-size risk loci in cervical dystonia. A genomewide association study (GWAS) was performed. British resident...
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