Article
Genetic relatedness among hepatitis A virus strains associated with food-borne outbreaks.
PloS one - 1 Jan 2013
Vaughan Gilberto, Xia Guoliang, Forbi Joseph C, Purdy Michael A, Rossi Lívia Maria Gonçalves, Spradling Philip R, Khudyakov Yury E
Abstract excerpt
The genetic characterization of hepatitis A virus (HAV) strains is commonly accomplished by sequencing subgenomic regions, such as the VP1/P2B junction. HAV genome is not extensively variable, thus presenting opportunity for sharing sequences of subgenomic regions among genetically unrelated isolates. The degree of misrepresentation of phylogenetic relationships by subgenomic regions is especially important for...
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