Article
Clinical outcomes after first-line EGFR inhibitor treatment for patients with NSCLC, EGFR mutation, and poor performance status.
Anticancer research - 1 Nov 2013
Okuma Yusuke, Hosomi Yukio, Nagamata Makoto, Yamada Yuko, Sekihara Kuniko, Kato Kan, Hishima Tsunekazu, Okamura Tatsuru
Abstract excerpt
BACKGROUND: The phase II NEJ001 trial suggested that gefitinib was active against advanced non-small cell lung cancer (NSCLC) even in patients with poor performance status (PS). Clinical response among the patients harboring epidermal growth factor receptor (EGFR) mutation with poor PS is fair; however, gefitinib does not have as much continued efficacy as in patients with good PS. This study has retrospectively...
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