Article
Increased level of organochlorine pesticides in chronic kidney disease patients of unknown etiology: role of GSTM1/GSTT1 polymorphism.
Chemosphere - 1 Feb 2014
Siddarth Manushi, Datta Sudip K, Mustafa Md, Ahmed Rafat S, Banerjee Basu D, Kalra Om P, Tripathi Ashok K
Abstract excerpt
Chronic kidney disease (CKD) of unknown etiology represents about 16% of CKD patients in Indian subcontinents and 10% worldwide. The aetiology of CKD of unknown etiology remains unclear though epidemiological studies indicate the involvement of the environmental toxins. Organochlorine pesticides (OCPs) have been detected in general population in India. It is possible that polymorphism of xenobiotic metabolizing...
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