Article
The novel coding region SNPs of PPARGC1A gene and their associations with growth traits in Chinese native cattle.
Molecular biology reports - 1 Jan 2014
Li Mijie, Liu Mei, Liu Dong, Lan Xianyong, Lei Chuzhao, Chen Hong
Abstract excerpt
The peroxisome proliferator-activated receptor gamma coactivator-1 alpha protein, encoded by the PPARGC1A gene, is a metabolic switch, which transcriptionally activates a complex pathway of mitochondrial biogenesis, lipid and glucose metabolism. Three SNPs (exon 3 c.396G>A, intron 9 c.1892 + 19C>T and exon 10 c.1971C>T) were found and identified in three Chinese native cattle breeds by PCR-SSCP, PCR-RFLP and DNA...
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