Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular stress pathways in pediatric bone marrow failure syndromes: many roads lead to neutropenia.

Pediatric research - 1 Jan 2014

Glaubach Taly, Minella Alex C, Corey Seth J

Abstract excerpt

The inherited bone marrow failure syndromes, like severe congenital neutropenia (SCN) and Shwachman-Diamond syndrome (SDS), provide unique insights into normal and impaired myelopoiesis. The inherited neutropenias are heterogeneous in both clinical presentation and genetic associations, and their causative mechanisms are not well established. SCN, for example, is a genetically heterogeneous syndrome associated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Aplastic
Share to Apoptosis
Share to Bone Marrow Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Bone Marrow Failure Disorders

Share to Hemoglobinuria, Paroxysmal

Share to Neutropenia

Share to Neutrophils

Share to Stress, Physiological

Source

Identifiers

PMID: 24192702
DOI: 10.1038/pr.2013.197

Genes

SDS
ELANE
GFI1
HAX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular stress pathways in pediatric bone marrow failure syndromes: many roads lead to neutropenia.PMID 24192702Read ↗

Pathogenic mechanisms and clinical implications of congenital neutropenia syndromesSemantic proximity Read ↗

Genetic defects in severe congenital neutropenia: emerging insights into life and death of human neutrophil granulocytes.Semantic proximity Read ↗

Congenital neutropeniaSemantic proximity Read ↗

Novel genetic etiologies of severe congenital neutropenia.Semantic proximity Read ↗

Mechanisms of leukemic transformation in congenital neutropeniaSemantic proximity Read ↗

Lessons from congenital neutropenia: 50 years of progress in understanding myelopoiesisSemantic proximity Read ↗

Discerning clinicopathological features of congenital neutropenia syndromes: an approach to diagnostically challenging differential diagnoses.Semantic proximity Read ↗

Genetic etiologies of severe congenital neutropenia.Semantic proximity Read ↗

The Molecular and Genetic Mechanisms of Inherited Bone Marrow Failure Syndromes: The Role of Inflammatory Cytokines in Their PathogenesisSemantic proximity Read ↗

Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cellsSemantic proximity Read ↗

Severe congenital neutropenia and the unfolded protein responseSemantic proximity Read ↗

Somatic mutations and clonal hematopoiesis in congenital neutropenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.