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Acquired Obesity Increases CD68 and Tumor Necrosis Factor-α and Decreases Adiponectin Gene Expression in Adipose Tissue: A Study in Monozygotic Twins

11 Apr 2006

Abstract excerpt

CONTEXT: Both acquired and genetic factors regulate adipose tissue function. OBJECTIVE: We determined whether adipose tissue mRNA expression is regulated by obesity, independently of genetic effects, by studying monozygotic (MZ) twins. DESIGN: Seventeen healthy pairs of MZ twins aged 24-27 yr (body mass index 20.0-33.9 kg/m(2), intrapair differences in body weight 0.1-24.7 kg), were identified from the...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 16608891
DOI: 10.1210/jc.2005-2848

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