Article
Isolation of human genomic DNA for genetic analysis from premature neonates: a comparison between newborn dried blood spots, whole blood and umbilical cord tissue.
BMC genetics - 29 Oct 2013
Rajatileka Shavanthi, Luyt Karen, El-Bokle Manal, Williams Maggie, Kemp Helena, Molnár Elek, Váradi Anikó
Abstract excerpt
BACKGROUND: Genotyping requires biological sample collection that must be reliable, convenient and acceptable for patients and clinicians. Finding the most optimal procedure of sample collection for premature neonates who have a very limited blood volume is a particular challenge. The aim of the current study was to evaluate the use of umbilical cord (UC) tissue and newborn dried blood spot (DBS)-extracted...
Topics
- Alleles
- Cohort Studies
- DNA
- Dried Blood Spot Testing
- Gene Frequency
- Genetic Techniques
- Genetic Testing
- Genome, Human
- Genotype
- Gestational Age
- Humans
- Infant, Newborn
- Polymerase Chain Reaction