Article
Klf1, a C2H2 zinc finger-transcription factor, is required for cell wall maintenance during long-term quiescence in differentiated G0 phase.
PloS one - 1 Jan 2013
Shimanuki Mizuki, Uehara Lisa, Pluskal Tomáš, Yoshida Tomoko, Kokubu Aya, Kawasaki Yosuke, Yanagida Mitsuhiro
Abstract excerpt
Fission yeast, Schizoaccharomyces pombe, is a model for studying cellular quiescence. Shifting to a medium that lacks a nitrogen-source induces proliferative cells to enter long-term G0 quiescence. Klf1 is a Krüppel-like transcription factor with a 7-amino acid Cys2His2-type zinc finger motif. The deletion mutant, ∆klf1, normally divides in vegetative medium, but proliferation is not restored after long-term G0...
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