Article
Low 25(OH) vitamin D3 levels are associated with adverse outcome in newly diagnosed, intensively treated adult acute myeloid leukemia.
Cancer - 15 Feb 2014
Lee Hun Ju, Muindi Josephia R, Tan Wei, Hu Qiang, Wang Dan, Liu Song, Wilding Gregory E, Ford Laurie A, Sait Sheila N J, Block Annemarie W, Adjei Araba A, Barcos Maurice, Griffiths Elizabeth A, Thompson James E, Wang Eunice S, Johnson Candace S, Trump Donald L, Wetzler Meir
Abstract excerpt
BACKGROUND: Several studies have suggested that low 25(OH) vitamin D3 levels may be prognostic in some malignancies, but no studies have evaluated their impact on treatment outcome in patients with acute myeloid leukemia (AML). METHODS: Vitamin D levels were evaluated in 97 consecutive, newly diagnosed, intensively treated patients with AML. MicroRNA expression profiles and single nucleotide polymorphisms (SNPs)...
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