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Reconciling Phylodynamics with Epidemiology: The Case of Dengue Virus in Southern Vietnam

22 Oct 2013

Abstract excerpt

Coalescent methods are widely used to infer the demographic history of populations from gene genealogies. These approaches-often referred to as phylodynamic methods-have proven especially useful for reconstructing the dynamics of rapidly evolving viral pathogens. Yet, population dynamics inferred from viral genealogies often differ widely from those observed from other sources of epidemiological data, such as...

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PMID: 24150038
DOI: 10.1093/molbev/mst203

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