Article
Altered antigenic profiling and infectivity of Porphyromonas gingivalis in smokers and non-smokers with periodontitis.
Journal of periodontology - 1 Jun 2014
Zeller Iris, Hutcherson Justin A, Lamont Richard J, Demuth Donald R, Gumus Pinar, Nizam Nejat, Buduneli Nurcan, Scott David A
Abstract excerpt
BACKGROUND: Cigarette smokers are more susceptible to periodontal diseases and are more likely to be infected with Porphyromonas gingivalis than non-smokers. Furthermore, smoking is known to alter the expression of P. gingivalis surface components and compromise immunoglobulin (Ig)G generation. The aim of this study is to evaluate whether the overall IgG response to P. gingivalis is suppressed in smokers in vivo...
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