Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation

doi:10.3324/haematol.2009.016436

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Article

Combining information regarding chromosomal aberrations t(4;14) and del(17p13) with the International Staging System classification allows stratification of myeloma patients undergoing autologous stem cell transplantation

10 Mar 2010

Abstract excerpt

BACKGROUND: Chromosomal abnormalities have been shown to play a major role in disease evolution of multiple myeloma. Specific changes in interphase cells can be detected by fluorescent in situ hybridization, which overcomes the problem of the lack of dividing cells required for conventional cytogenetics. DESIGN AND METHODS: We analyzed the prognostic value of 12 frequent chromosomal abnormalities detected by...

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PMID: 20220069
DOI: 10.3324/haematol.2009.016436

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