Article
Robust estimates of divergence times and selection with a poisson random field model: a case study of comparative phylogeographic data.
Genetics - 1 Jan 2014
Amei Amei, Smith Brian Tilston
Abstract excerpt
Mutation frequencies can be modeled as a Poisson random field (PRF) to estimate speciation times and the degree of selection on newly arisen mutations. This approach provides a quantitative theory for comparing intraspecific polymorphism with interspecific divergence in the presence of selection and can be used to estimate population genetic parameters. Although the original PRF model has been extended to more...
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