Targeted resequencing of candidate genes reveals novel variants associated with severe Behçet's uveitis.

Abstract excerpt

Behçet's disease (BD) is a chronic systemic inflammatory disorder characterized by four major manifestations: recurrent uveitis, oral and genital ulcers and skin lesions. To identify some pathogenic variants associated with severe Behçet's uveitis, we used targeted and massively parallel sequencing methods to explore the genetic diversity of target regions. A solution-based target enrichment kit was designed to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aged
• Share to Behcet Syndrome
• Share to Case-Control Studies