Article
Hereditary ovarian and breast cancer: what have we learned?
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Nov 2013
Lynch H T, Snyder C, Casey M J
Abstract excerpt
An autosomal-dominant inherited trait predisposing women to both breast cancer (BC) and ovarian cancer (OC) was first described in 1971. Subsequent strides were made in identifying mutations in the eventually cloned genes BRCA1 and BRCA2 as being responsible for hereditary BC and OC (HBOC) in man...
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