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Article

Complex c-di-GMP signaling networks mediate transition between virulence properties and biofilm formation in Salmonella enterica serovar Typhimurium.

PloS one - 1 Jan 2011

Ahmad Irfan, Lamprokostopoulou Agaristi, Le Guyon Soazig, Streck Elena, Barthel Melanie, Peters Verena, Hardt Wolf-Dieter, Römling Ute

Abstract excerpt

Upon Salmonella enterica serovar Typhimurium infection of the gut, an early line of defense is the gastrointestinal epithelium which senses the pathogen and intrusion along the epithelial barrier is one of the first events towards disease. Recently, we showed that high intracellular amounts of the secondary messenger c-di-GMP in S. typhimurium inhibited invasion and abolished induction of a pro-inflammatory...

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PMID: 22164276
DOI: 10.1371/journal.pone.0028351
PMCID: PMC3229569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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