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Article

An investigation of the effects of FGFR2 and B7-H4 polymorphisms in breast cancer.

Journal of cancer research and therapeutics - 1 Jan 2000

Ozgöz Asuman, Samli Hale, Oztürk Kuyaș Hekimler, Orhan Bülent, Icduygu Fadime Mutlu, Aktepe Fatma, Imirzalioglu Necat

Abstract excerpt

INTRODUCTION: Polymorphisms in FGFR2 are important markers for breast cancer susceptibility in the general population. CHEK2 and FGFR2 polymorphisms with known susceptibility alleles of BRCA1, BRCA2, PTEN, and TP53, can be investigated as potential modifiers of high penetrant risk alleles. Although the B7-H4 gene is highly expressed in many different tumors, there is one published study showing the association of...

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Source

Identifiers

PMID: 24125968
DOI: 10.4103/0973-1482.114434

Genes

FGFR2
BRCA1
BRCA2
CHEK2
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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