Article
On the use of dexamethasone-loaded liposomes to induce the osteogenic differentiation of human mesenchymal stem cells.
Journal of tissue engineering and regenerative medicine - 1 Sept 2015
Monteiro Nelson, Martins Albino, Ribeiro Diana, Faria Susana, Fonseca Nuno A, Moreira João N, Reis Rui L, Neves Nuno M
Abstract excerpt
Stem cells have received considerable attention by the scientific community because of their potential for tissue engineering and regenerative medicine. The most frequently used method to promote their differentiation is supplementation of the in vitro culture medium with growth/differentiation factors (GDFs). The limitations of that strategy caused by the short half-life of GDFs limit its efficacy in vivo and...
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