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Article

MED12 related disorders.

American journal of medical genetics. Part A - 1 Nov 2013

Graham John M, Schwartz Charles E

Abstract excerpt

MED12: is a member of the large Mediator complex, which has a critical and central role in RNA polymerase II transcription. As a multiprotien complex, Mediator regulates signals involved in cell growth, development, and differentiation, and it is involved in a protein network required for extraneuronal gene silencing and also functions as a direct suppressor of Gli3-dependent Sonic hedgehog signaling. This may...

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Source

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Identifiers

PMID: 24123922
DOI: 10.1002/ajmg.a.36183
PMCID: PMC3839301

Genes

MED12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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