Article
Choosing Alzheimer's disease prevention clinical trial populations.
Neurobiology of aging - 1 Mar 2014
Grill Joshua D, Monsell Sarah E
Abstract excerpt
To assist investigators in making design choices, we modeled Alzheimer's disease prevention clinical trials. We used longitudinal Clinical Dementia Rating Scale Sum of Boxes data, retention rates, and the proportions of trial-eligible cognitively normal participants age 65 and older in the National Alzheimer's Coordinating Center Uniform Data Set to model trial sample sizes, the numbers needed to enroll to...
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