Article
A novel peptide-modified and gene-activated biomimetic bone matrix accelerating bone regeneration.
Journal of biomedical materials research. Part A - 1 Aug 2014
Pan Haitao, Zheng Qixin, Yang Shuhua, Guo Xiaodong, Wu Bin, Zou Zhenwei, Duan Zhixia
Abstract excerpt
The osteogenic differentiation of bone marrow stromal cells (BMSCs) can be regulated by systemic or local growth factor, especially by transforming growth factor beta 1 (TGF-β1). However, how to maintain the bioactivity of exogenous TGF-β1 is a great challenge due to its short half-life time. The...
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