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Article

Autism traits in the RASopathies.

Journal of medical genetics - 1 Jan 2014

Adviento Brigid, Corbin Iris L, Widjaja Felicia, Desachy Guillaume, Enrique Nicole, Rosser Tena, Risi Susan, Marco Elysa J, Hendren Robert L, Bearden Carrie E, Rauen Katherine A, Weiss Lauren A

Abstract excerpt

BACKGROUND: Mutations in Ras/mitogen-activated protein kinase (Ras/MAPK) pathway genes lead to a class of disorders known as RASopathies, including neurofibromatosis type 1 (NF1), Noonan syndrome (NS), Costello syndrome (CS), and cardio-facio-cutaneous syndrome (CFC). Previous work has suggested potential genetic and phenotypic overlap between dysregulation of Ras/MAPK signalling and autism spectrum disorders...

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Identifiers

PMID: 24101678
DOI: 10.1136/jmedgenet-2013-101951
PMCID: PMC4230531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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