Article
Genetic polymorphism of interleukin-16 and risk of nasopharyngeal carcinoma.
Clinica chimica acta; international journal of clinical chemistry - 1 Nov 2009
Gao Lin-Bo, Liang Wei-Bo, Xue Hui, Rao Li, Pan Xin-Min, Lv Mei-Li, Bai Peng, Fang Wen-Liang, Liu Jin, Liao Miao, Zhang Lin
Abstract excerpt
BACKGROUND: Common genetic variants in inflammatory cytokine genes can affect the risk of developing nasopharyngeal carcinoma (NPC). Interleukin-16 (IL-16), a pro-inflammatory cytokine, plays a pivotal role in inflammatory diseases as well as in the pathogenesis of tumors. METHODS: We analyzed rs4778889 T/C, rs11556218 T/G, and rs4072111 C/T polymorphisms of IL-16 in 206 patients with NPC and 373 healthy controls...
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