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Article

DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation.

BMC genomics - 5 Oct 2013

Das Radhika, Lee Yew Kok, Strogantsev Ruslan, Jin Shengnan, Lim Yen Ching, Ng Poh Yong, Lin Xueqin Michelle, Chng Keefe, Yeo George Sh, Ferguson-Smith Anne C, Ding Chunming

Abstract excerpt

BACKGROUND: Genomic imprinting is an epigenetically regulated process wherein genes are expressed in a parent-of-origin specific manner. Many imprinted genes were initially identified in mice; some of these were subsequently shown not to be imprinted in humans. Such discrepancy reflects developmental, morphological and physiological differences between mouse and human tissues. This is particularly relevant for...

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PMID: 24094292
DOI: 10.1186/1471-2164-14-685
PMCID: PMC3829101

Genes

DNMT1

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