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MiR-34a is up-regulated in response to low dose, low energy X-ray induced DNA damage in breast cells

5 Oct 2013

Abstract excerpt

BACKGROUND: MicroRNAs are non-coding RNAs involved in the regulation of gene expression including DNA damage responses. Low doses of low energy X-ray radiation, similar to those used in mammographic exams, has been described to be genotoxic. In the present work we investigated the expression of miR-34a; a well described p53-regulated miRNA implicated in cell responses to X-ray irradiation at low doses. METHODS:...

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PMID: 24094113
DOI: 10.1186/1748-717x-8-231

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