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Article

A single amino acid in the F2 subunit of respiratory syncytial virus fusion protein alters growth and fusogenicity.

The Journal of general virology - 1 Dec 2013

Lawlor Heather A, Schickli Jeanne H, Tang Roderick S

Abstract excerpt

Respiratory syncytial virus (RSV) causes severe lower respiratory tract infection in children, especially in infants less than 1 year of age. There are currently no licensed vaccines against RSV. rA2ΔM2-2 is a promising live-attenuated vaccine candidate that is currently being evaluated in the clinic. Attenuation of rA2ΔM2-2 is achieved by a single deletion of the M2-2 gene, which disrupts the balance between...

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Identifiers

PMID: 24092758
DOI: 10.1099/vir.0.055368-0
PMCID: PMC3836501

Genes

CPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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