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Lineage-tracing methods and the kidney

2 Oct 2013

Abstract excerpt

The kidney is a complex organ with over 30 different cell types, and understanding the lineage relationships between these cells is challenging. During nephrogenesis, a central question is how the coordinated morphogenesis, growth, and differentiation of distinct cell types leads to development of a functional organ. In mature kidney, understanding cell division and fate during injury, regeneration and aging are...

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PMID: 24088959
DOI: 10.1038/ki.2013.368

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