Article
Genetic variation in the vitamin D receptor, plasma 25-hydroxyvitamin D, and biomarkers of cardiometabolic disease in Caucasian young adults.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2013
García-Bailo Bibiana, Jamnik Joseph, Da Costa Laura A, Badawi Alaa, El-Sohemy Ahmed
Abstract excerpt
BACKGROUND/AIMS: Vitamin D regulates gene transcription by binding to the vitamin D receptor (VDR), potentially affecting cardiometabolic disease risk. However, studies of 25-hydroxyvitamin D [25(OH)D] and cardiometabolic disease are inconsistent. Inconsistencies may result from unaccounted for interactions between VDR genetic variants and 25(OH)D. We examined the effect of 25(OH)D on the association between VDR...
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