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Article

JMJD2B Promotes Epithelial–Mesenchymal Transition by Cooperating with β-Catenin and Enhances Gastric Cancer Metastasis

28 Sept 2013

Abstract excerpt

PURPOSE: This study investigated the role of histone demethylase Jumonji domain-containing protein 2B (JMJD2B) in promoting epithelial-mesenchymal transition (EMT) and underlying molecular mechanisms in the progression of gastric cancer. EXPERIMENTAL DESIGN: The induction of EMT by JMJD2B in gastric cancer cells and its underlying mechanisms were examined by a series of assays. In vivo and in vitro assays were...

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Identifiers

PMID: 24077348
DOI: 10.1158/1078-0432.ccr-13-0254

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