Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.

doi:10.1165/rcmb.2013-0261OC

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.

American journal of respiratory cell and molecular biology - 1 Mar 2014

Sun Xingshen, Olivier Alicia K, Liang Bo, Yi Yaling, Sui Hongshu, Evans Turan I A, Zhang Yulong, Zhou Weihong, Tyler Scott R, Fisher John T, Keiser Nicholas W, Liu Xiaoming, Yan Ziying, Song Yi, Goeken J Adam, Kinyon Joann M, Fligg Danielle, Wang Xiaoyan, Xie Weiliang, Lynch Thomas J, Kaminsky Paul M, Stewart Zoe A, Pope R Marshall, Frana Timothy, Meyerholz David K, Parekh Kalpaj, Engelhardt John F

Abstract excerpt

Chronic bacterial lung infections in cystic fibrosis (CF) are caused by defects in the CF transmembrane conductance regulator chloride channel. Previously, we described that newborn CF transmembrane conductance regulator-knockout ferrets rapidly develop lung infections within the first week of life. Here, we report a more slowly progressing lung bacterial colonization phenotype observed in juvenile to adult CF...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Animals, Genetically Modified

Share to Cystic Fibrosis

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to Ferrets

Share to Intestines

Share to Lung

Share to Respiratory Tract Infections

Source

Open in PubMed Open full text

Identifiers

PMID: 24074402
DOI: 10.1165/rcmb.2013-0261OC
PMCID: PMC4068938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.PMID 24074402Read ↗

Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis.Semantic proximity Read ↗

The Lung Microbiome in Young Children with Cystic Fibrosis: A Prospective Cohort StudySemantic proximity Read ↗

Directly Sampling the Lung of a Young Child with Cystic Fibrosis Reveals Diverse MicrobiotaSemantic proximity Read ↗

Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and DivergencesSemantic proximity Read ↗

Airway microbiota across age and disease spectrum in cystic fibrosisSemantic proximity Read ↗

Lung microbiota across age and disease stage in cystic fibrosisSemantic proximity Read ↗

Lung infections associated with cystic fibrosis.Semantic proximity Read ↗

Divergence of bacterial communities in the lower airways of CF patients in early childhoodSemantic proximity Read ↗

Airway disease phenotypes in animal models of cystic fibrosis.Semantic proximity Read ↗

Cystic fibrosis transmembrane conductance regulator knockout mice exhibit aberrant gastrointestinal microbiotaSemantic proximity Read ↗

Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at BirthSemantic proximity Read ↗

Lung disease in mice with cystic fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.