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Article

FGF2-induced effects on transcriptome associated with regeneration competence in adult human fibroblasts

26 Sept 2013

Abstract excerpt

BACKGROUND: Adult human fibroblasts grown in low oxygen and with FGF2 supplementation have the capacity to tip the healing outcome of skeletal muscle injury - by favoring regeneration response in vivo over scar formation. Here, we compare the transcriptomes of control adult human dermal fibroblasts and induced regeneration-competent (iRC) fibroblasts to identify transcriptional changes that may be related to...

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PMID: 24066673
DOI: 10.1186/1471-2164-14-656

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