Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification.

doi:10.1371/journal.pone.0073851

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Article

Extensive diversity of Streptococcus pyogenes in a remote human population reflects global-scale transmission rather than localised diversification.

PloS one - 1 Jan 2013

Towers Rebecca J, Carapetis Jonathan R, Currie Bart J, Davies Mark R, Walker Mark J, Dougan Gordon, Giffard Philip M

Abstract excerpt

The Indigenous population of the Northern Territory of Australia (NT) suffers from a very high burden of Streptococcus pyogenes disease, including cardiac and renal sequelae. The aim of this study was to determine if S. pyogenes isolated from this population represent NT endemic strains, or conversely reflect strains with global distribution. emm sequence typing data were used to select 460 S. pyogenes isolates...

Topics

Alleles
Australia
Humans
Multilocus Sequence Typing
Streptococcal Infections
Streptococcus pyogenes

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PMID: 24066079
DOI: 10.1371/journal.pone.0073851
PMCID: PMC3774777

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