Article
Whole genome sequencing reveals extensive community-level transmission of group A Streptococcus in remote communities.
Epidemiology and infection - 1 Jul 2016
Bowen A C, Harris T, Holt D C, Giffard P M, Carapetis J R, Campbell P T, McVERNON J, Tong S Y C
Abstract excerpt
Impetigo is common in remote Indigenous children of northern Australia, with the primary driver in this context being Streptococcus pyogenes [or group A Streptococcus (GAS)]. To reduce the high burden of impetigo, the transmission dynamics of GAS must be more clearly elucidated. We performed whole genome sequencing on 31 GAS isolates collected in a single community from children in 11 households with ⩾2...
Topics
- Australia
- Child
- Child, Preschool
- Disease Transmission, Infectious
- Family Characteristics
- Female
- Genetic Variation
- Genome, Bacterial
- Genotype
- Humans
- Impetigo
- Male
- Molecular Epidemiology
- Multilocus Sequence Typing