Subcellular fate of the int-2 oncoprotein is determined by choice of initiation codon.

doi:10.1038/343662a0

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Article

Subcellular fate of the int-2 oncoprotein is determined by choice of initiation codon.

Nature - 15 Feb 1990

Acland P, Dixon M, Peters G, Dickson C

Abstract excerpt

Fibroblast growth factors (FGFs) have been implicated in many aspects of cell growth and differentiation both in normal and neoplastic settings. For example, the mouse int-2 gene, which encodes an FGF-related product, is a frequent target of proviral activation in carcinomas induced by mouse mamm...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Line
Cell Membrane
Cell Nucleus
Cloning, Molecular
Codon
Fibroblast Growth Factor 3
Fibroblast Growth Factors
Genetic Vectors
Mice
Microsomes
Molecular Sequence Data
Mutation
Peptide Chain Initiation, Translational
Protein Biosynthesis
Proto-Oncogene Proteins

Source

Open in PubMed

Identifiers

PMID: 2406607
DOI: 10.1038/343662a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2406607-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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