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Article

A polymorphism at the 3'-UTR region of the aromatase gene is associated with the efficacy of the aromatase inhibitor, anastrozole, in metastatic breast carcinoma.

International journal of molecular sciences - 13 Sept 2013

Liu Lei, Bai Yu-Xian, Zhou Jian-Hua, Sun Xiu-Wei, Sui Hong, Zhang Wen-Jie, Yuan Heng-Heng, Xie Rui, Wei Xiao-Li, Zhang Ting-Ting, Huang Peng, Li Yan-Jing, Wang Jing-Xuan, Zhao Shu, Zhang Qing-Yuan

Abstract excerpt

Estrogen-related genes and the fat mass and obesity-associated (FTO) gene play a critical role in estrogen metabolism, and those polymorphisms are associated with a poor prognosis in breast cancer. However, little is known about the association between these polymorphisms and the efficacy of anas...

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Source

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Identifiers

PMID: 24065098
DOI: 10.3390/ijms140918973
PMCID: PMC3794816

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24065098-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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