Article
[Growth and mutation of Escherichia coli with suicide gene circuit based on quorum sensing].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Jun 2013
Gao Qi, Zheng Xuesong
Abstract excerpt
Constructing robust gene circuits is a fundamental work for synthetic biology. Bacteria with suicide gene circuit based on quorum-sensing will kill themselves in a controllable pattern upon certain cell density. In the media of different IPTG inducer concentration, we observed the growth and suicidal behavior of the Escherichia coli. Top10F' with such gene circuit, screened the mutants and determined their...
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