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In vitro attenuated Histomonas meleagridis does not revert to virulence, following serial in vivo passages in turkeys or chickens.

Vaccine - 4 Nov 2013

Sulejmanovic Tarik, Liebhart Dieter, Hess Michael

Abstract excerpt

The efficacy of vaccinating poultry against histomonosis was demonstrated recently. In the present study, the reversion to virulence and the residual pathogenicity of an in vitro attenuated, clonal strain of Histomonas meleagridis were tested in two consecutive experiments. The European Pharmcopoeia (Ph. Eur.) monograph for testing such features for coccidiosis live vaccines in chickens has served as a guideline....

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PMID: 24055087
DOI: 10.1016/j.vaccine.2013.08.098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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