Article
Chemical Diversity of Aspergillus alliaceus Phenotypes: Discovery of Brominated Bianthrones with Activity against Triple-Negative Breast Cancer Cell Lines.
Chembiochem : a European journal of chemical biology - 16 Oct 2024
Mandelare Paige E, Yee Samantha S, Icenhour Daniel G, Kaweesa Elizabeth N, McCauley Mark, Risinger April L, Rudolf Jeffrey D, Loesgen Sandra
Abstract excerpt
Marine-derived fungi have emerged as a source for novel metabolites with a broad range of bioactivities. However, accessing the full potential of fungi under standard laboratory conditions remains challenging. LC-MS-based metabolomics in combination with varied culture conditions is a fast and powerful tool to detect new metabolites. Here, three developmental forms of the marine-derived fungus Aspergillus...
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