Article
Modifying disease in cystic fibrosis: current and future therapies on the horizon.
Current opinion in pulmonary medicine - 1 Nov 2013
Ong Thida, Ramsey Bonnie W
Abstract excerpt
PURPOSE OF REVIEW: Recent therapies directed at proximal targets within cystic fibrosis (CF) pathophysiology hold potential to modulate disease. This review highlights recent clinical trials and future therapies focused on these early steps of disease. RECENT FINDINGS: Recent approval of a CF transmembrane conductance regulator (CFTR) protein modulator, ivacaftor (Kalydeco), has ignited a wave of investigations...
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