Article
Epigenetic memory emerging from integrated transcription bursts.
Biophysical journal - 17 Sept 2013
Kurz Volker, Nelson Edward M, Perry Nicolas, Timp Winston, Timp Gregory
Abstract excerpt
Some autonomous bacteria coordinate their actions using quorum-sensing (QS) signals to affect gene expression. However, noise in the gene environment can compromise the cellular response. By exercising precise control over a cell's genes and its microenvironment, we have studied the key positive autoregulation element by which the lux QS system integrates noisy signals into an epigenetic memory. We observed...
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