Diversity of the O-superfamily conotoxins from Conus miles.

doi:10.1002/psc.802

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Article

Diversity of the O-superfamily conotoxins from Conus miles.

Journal of peptide science : an official publication of the European Peptide Society - 1 Jan 2007

Luo Sulan, Zhangsun Dongting, Feng Jiancheng, Wu Yong, Zhu Xiaopeng, Hu Yuanyan

Abstract excerpt

Conopeptides display prominent features of hypervariability and high selectivity of large gene families that mediate interactions between organisms. Remarkable sequence diversity of O-superfamily conotoxins was found in a worm-hunting cone snail Conus miles. Five novel cDNA sequences encoding O-superfamily precursor peptides were identified in C. miles native to Hainan by RT-PCR and 3'-RACE. They share the common...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Conotoxins
Conus Snail
DNA, Complementary
Genetic Variation
Molecular Sequence Data
Multigene Family
Protein Isoforms
Protein Precursors
Protein Sorting Signals
Sequence Alignment
Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 17106905
DOI: 10.1002/psc.802

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