Article
A three-dimensional co-culture model of the aortic valve using magnetic levitation.
Acta biomaterialia - 1 Jan 2014
Tseng Hubert, Balaoing Liezl R, Grigoryan Bagrat, Raphael Robert M, Killian T C, Souza Glauco R, Grande-Allen K Jane
Abstract excerpt
The aortic valve consists of valvular interstitial cells (VICs) and endothelial cells (VECs). While these cells are understood to work synergistically to maintain leaflet structure and valvular function, few co-culture models of these cell types exist. In this study, aortic valve co-cultures (AVCCs) were assembled using magnetic levitation and cultured for 3 days. Immunohistochemistry and quantitative...
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