Developmental programming of growth: genetic variant in GH2 gene encoding placental growth hormone contributes to adult height determination.

doi:10.1016/j.placenta.2013.08.012

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Article

Developmental programming of growth: genetic variant in GH2 gene encoding placental growth hormone contributes to adult height determination.

Placenta - 1 Nov 2013

Timasheva Y, Putku M, Kivi R, Kožich V, Männik J, Laan M

Abstract excerpt

INTRODUCTION: Given the physiological role of placental growth hormone (PGH) during intrauterine development and growth, genetic variation in the coding Growth hormone 2 (GH2) gene may modulate developmental programming of adult stature. Two major GH2 variants were described worldwide, determined by single polymorphism (rs2006123; c.171 + 50C > A). We sought to study whether GH2 variants may contribute to adult...

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PMID: 24035309
DOI: 10.1016/j.placenta.2013.08.012
PMCID: PMC3820034

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