Article
Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species.
eLife - 3 Sept 2013
Rosselló Ricardo Antonio, Chen Chun-Chun, Dai Rui, Howard Jason T, Hochgeschwender Ute, Jarvis Erich D
Abstract excerpt
Cells are fundamental units of life, but little is known about evolution of cell states. Induced pluripotent stem cells (iPSCs) are once differentiated cells that have been re-programmed to an embryonic stem cell-like state, providing a powerful platform for biology and medicine. However, they have been limited to a few mammalian species. Here we found that a set of four mammalian transcription factor genes used...
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