Article
Splicing variants of SERPINA1 gene in ovine milk: characterization of cDNA and identification of polymorphisms.
PloS one - 1 Jan 2013
Marchitelli Cinzia, Crisà Alessandra, Mostarda Elisa, Napolitano Francesco, Moioli Bianca
Abstract excerpt
The serine protease inhibitor, clade A, member 1 (SERPINA1) is the gene for a protein called alpha-1-antitrypsin (AAT), which is a member of the serine protease inhibitor (serpin) superfamily of proteins. By conformational change, serpins control several chemical reactions inhibiting the activity of proteases. AAT is the most abundant endogenous serpin in blood circulation and it is present in relatively high...
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