Article
Phospholipid-dependent procoagulant activity is highly expressed by circulating microparticles in patients with essential thrombocythemia.
American journal of hematology - 1 Jan 2014
Marchetti Marina, Tartari Carmen J, Russo Laura, Panova-Noeva Marina, Leuzzi Annamaria, Rambaldi Alessandro, Finazzi Guido, Woodhams Barry, Falanga Anna
Abstract excerpt
This study evaluates the functional procoagulant features of plasma microparticle (MP) to explore the MP contribution to the hypercoagulable state of patients with essential thrombocythemia (ET). Platelet-free plasma samples were obtained from 73 ET patients (37 positive for the JAK2V617F mutation) and 72 control subjects. The calibrated automated thrombogram (CAT) was performed in plasma samples to determine...
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